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KMID : 0361020160590070522
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Korean Journal of Otolaryngology - Head and Neck Surgery
2016 Volume.59 No. 7 p.522 ~ p.526
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Clinical Features and Outcomes of a Rare Nasal Cavity Tumor Glomangiopericytoma
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Han Seung-Hoon
Jin Young-Ju
Hong Seung-No
Kim Dae-Woo
Park Min-Hyun
Rhee Chae-Seo
Lee Chul-Hee
Won Tae-Bin
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Abstract
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Background and Objectives : Glomangiopericytoma falls within the category of borderline low-malignant-potential soft tissue tumors of the nose and paranasal sinuses. It is a rare tumor arising from the pericytes surrounding capillaries, and accounts for less than 0.5% of all sinonasal tumors. The aim of this study was to analyze the clinical manifestation and surgical outcomes of the glomangiopericytoma in the nasal cavity.
Subjects and Method : Medical records of eight patients who were surgically managed for glomangiopericytoma of the nose and paranasal sinuses from 2000 to 2015 were retrospectively reviewed. Clinical features, size, Immunohistochemical staining, extent of surgery, adjuvant treatment, and recurrence were evaluated.
Results : Eight patients, 3 males and 5 females, were enrolled, with the mean age of 54.7 years old. The most common symptom of glomangiopericytoma was ipsilateral nasal obstruction. All patients got surgical treatment, and one patient received radiation to the surgical site, whose margin of resection was positive. The mean follow-up period was 39.5 months (3-176 months). During the follow-up period, one patient was found to have a positive resection margin.
Conclusion : The surgical outcome shows that complete initial excision is important to prevent recurrence. Furthermore, adjuvant radiation therapy may also be a reasonable option for some patients with margin involvement.
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KEYWORD
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Hemangiopericytoma, Paranasal sinus neoplasms, Recurrence
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